Gray and white matter structures in the midcingulate cortex region contribute to body mass index in Chinese young adults.

ABSTRACT: Overweight and obesity are rapidly becoming a central public health challenge around the world. Previous studies have suggested that elevated Body Mass Index (BMI) might be associated with structural changes in both gray and white matter, but this association is still not well understood. The present study aimed to investigate the relationship between BMI and brain structure with a relatively large sample of young adults (N = 336) in a small age range (20 ± 1 years). Voxel-based morphometry results showed significant negative correlations between BMI and gray-matter volumes in the midcingulate cortex (MCC), left orbital frontal cortex, and left ventromedial prefrontal cortex. There was also a significant negative correlation between BMI and white matter integrity as indexed by fractional a

SUBMITTER: He Q 

PROVIDER: S-EPMC3995892 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature