Phage infection of an environmentally relevant marine bacterium alters host metabolism and lysate composition.

ABSTRACT: Viruses contribute to the mortality of marine microbes, consequentially altering biological species composition and system biogeochemistry. Although it is well established that host cells provide metabolic resources for virus replication, the extent to which infection reshapes host metabolism at a global level and the effect of this alteration on the cellular material released following viral lysis is less understood. To address this knowledge gap, the growth dynamics, metabolism and extracellular lysate of roseophage-infected Sulfitobacter sp. 2047 was studied using a variety of techniques, including liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based metabolomics. Quantitative estimates of the total amount of carbon and nitrogen sequestered into particulate biomass indicate t

SUBMITTER: Ankrah NY 

PROVIDER: S-EPMC3996693 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature