Clinical features of isolated gestational proteinuria progressing to pre-eclampsia: retrospective observational study.

ABSTRACT:

Objectives

Some women with isolated gestational proteinuria (IGP) later develop hypertension and are diagnosed with pre-eclampsia (PE). This study was performed to determine whether clinical features of such proteinuria preceding PE (P-PE) differ from those of other PE (O-PE).

Design

Retrospective observational study after approval of the institutional review board of ethics.

Setting

A single university hospital. Proteinuria was defined as a protein-to-creatinine ratio (mg/mg; P/Cr) of ≥0.27 in the spot urine specimen. IGP was defined as proteinuria in the absence of hypertension. P-PE was defined as PE in which proteinuria preceded hypertension by more than 2 days.

Participants

All of 10 and 18 consecutive women with P-PE and O-PE, respectively, who gave birth

SUBMITTER: Akaishi R 

PROVIDER: S-EPMC3996810 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature