The potential role of NT-proBNP in screening for and predicting prognosis in heart failure: a survival analysis.

ABSTRACT:

Objective

To determine the potential role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in screening for and predicting prognosis in heart failure by examining diagnosis and survival of patients with a raised NT-proBNP at screening.

Design

Survival analysis.

Setting

Prospective substudy of the Echocardiographic Heart of England Screening study (ECHOES) to investigate 10-year survival in participants with an NT-proBNP level at baseline.

Participants

594 participants took part in the substudy. Records of all participants in the ECHOES cohort were flagged during the screening phase which ended on 25 February 1999. All deaths until 25 February 2009 were coded.

Outcome measures

Logistic regression was used to examine whether NT-proBNP is useful in

SUBMITTER: Taylor CJ 

PROVIDER: S-EPMC3996821 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature