Statistical modeling approach to quantitative analysis of interobserver variability in breast contouring.

ABSTRACT:

Purpose

To develop a new approach for interobserver variability analysis.

Methods and materials

Eight radiation oncologists specializing in breast cancer radiation therapy delineated a patient's left breast "from scratch" and from a template that was generated using deformable image registration. Three of the radiation oncologists had previously received training in Radiation Therapy Oncology Group consensus contouring for breast cancer atlas. The simultaneous truth and performance level estimation algorithm was applied to the 8 contours delineated "from scratch" to produce a group consensus contour. Individual Jaccard scores were fitted to a beta distribution model. We also applied this analysis to 2 or more patients, which were contoured by 9 breast radiation oncologists f

SUBMITTER: Yang J 

PROVIDER: S-EPMC3997068 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature