Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics.

ABSTRACT: Multispectral imaging is a highly desirable modality for material-based analysis in diverse areas such as food production and processing, satellite-based reconnaissance, and biomedical imaging. Here, we present nanofilter-based multispectral videography (nMSV) in the 700 to 950 nm range made possible by the tunable extraordinary-optical-transmission properties of 3D metallic nanostructures. Measurements made with nMSV during a bolus injection of an intravascular tracer in the ear of a piglet resulted in spectral videos of the microvasculature. Analysis of the multispectral videos generated contrast measurements representative of arterial pulsation, the distribution of microvascular transit times, as well as a separation of the venous and arterial signals arising from within the tissue. The

SUBMITTER: Najiminaini M 

PROVIDER: S-EPMC3998030 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature