Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis.

ABSTRACT:

Background

Optimal selection of blood donors is of paramount importance in ensuring the safety of blood products. The current selection process is concerned principally with the safety of the blood donor and the safety of the patient that receives the blood. Recent evidence suggests that the characteristics of the donor may affect transfusion outcomes for the recipient.

Methods

We will conduct a systematic review of the association between major blood donor characteristics and red blood cell (RBC) transfusion outcomes. The primary objective is to assess the association of blood donor characteristics and the risk of adverse short-term and long-term clinical outcomes after RBC transfusion. We will search MEDLINE, EMBASE, Cochrane Central databases, as well as perform manual se

SUBMITTER: Chasse M 

PROVIDER: S-EPMC3998188 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature