A Simplified Approach for Simultaneous Measurements of Wavefront Velocity and Curvature in the Heart Using Activation Times.

ABSTRACT: The velocity and curvature of a wave front are important factors governing the propagation of electrical activity through cardiac tissue, particularly during heart arrhythmias of clinical importance such as fibrillation. Presently, no simple computational model exists to determine these values simultaneously. The proposed model uses the arrival times at four or five sites to determine the wave front speed (v), direction (θ), and radius of curvature (ROC) (r₀). If the arrival times are measured, then v, θ, and r₀ can be found from differences in arrival times and the distance between these sites. During isotropic conduction, we found good correlation between measured values of the ROC r₀ and the distance from the unipolar s

SUBMITTER: Mazeh N 

PROVIDER: S-EPMC3998731 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature