Stimulus-response mappings shape inhibition processes: a combined EEG-fMRI study of contextual stopping.

ABSTRACT: Humans are rarely faced with one simple task, but are typically confronted with complex stimulus constellations and varying stimulus-relevance in a given situation. Through modifying the prototypical stop-signal task and by combined recording and analysis of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), we studied the effects of stimulus relevance for the generation of a response or its inhibition. Stimulus response mappings were modified by contextual cues, indicating which of two different stimuli following a go stimulus was relevant for stopping. Overall, response inhibition, that is comparing successful stopping to a stop-signal against go-signal related processes, was associated with increased activity in right inferior and left midfrontal regions, as

SUBMITTER: Lavallee CF 

PROVIDER: S-EPMC3999100 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature