Computerized counseling reduces HIV-1 viral load and sexual transmission risk: findings from a randomized controlled trial.

ABSTRACT:

Objective

Evaluate a computerized intervention supporting antiretroviral therapy (ART) adherence and HIV transmission prevention.

Design

Longitudinal randomized controlled trial.

Settings

An academic HIV clinic and a community-based organization in Seattle.

Subjects

In a total of 240 HIV-positive adults on ART, 209 completed 9-month follow-up (87% retention).

Intervention

Randomization to computerized counseling or assessment only, 4 sessions over 9 months.

Main outcome measures

HIV-1 viral suppression, and self-reported ART adherence and transmission risks, compared using generalized estimating equations.

Results

Overall, intervention participants had reduced viral load: mean 0.17 log10 decline, versus 0.13 increase in controls, P = 0.053,

SUBMITTER: Kurth AE 

PROVIDER: S-EPMC3999203 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature