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Association of BDNF and COMT genotypes with cognitive processing of anti-smoking PSAs.


ABSTRACT: Anti-smoking public service announcements (PSAs) often use persuasive arguments to attempt to influence attitudes about smoking. The persuasiveness of a PSA has previously been associated with factors that influence the cognitive processing of its message. Genetic factors that influence cognitive processing might thus affect individuals' responses to the persuasive arguments presented in PSAs. In the present study, we examined polymorphisms in the genes encoding brain-derived neurotrophic factor (BDNF Val66Met) and catechol-O-methyltransferase (COMT Val158Met), which affect cognitive processing in the prefrontal cortex, to identify genetic factors associated with self-reported outcomes of message processing, perceived effectiveness and quitting intentions among smokers viewing PSAs. A tota

SUBMITTER: Falcone M 

PROVIDER: S-EPMC4000094 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature