Patient choice as a driver of medication-switching in non-adherent individuals with bipolar disorder.

ABSTRACT:

Objective

Psychotropic-related weight gain is a common concern among patients with bipolar disorder (BD). This concern affects satisfaction with treatment and may lead to non-adherence and relapse. This was a 12-week, uncontrolled prospective trial of patient-choice-facilitated ziprasidone switching among non-adherent BD patients with weight concerns. This study was conducted from January 2011 to July 2012.

Method

Patients were asked to identify the "offending" BD medication which they believed was causing weight problems, and this agent was replaced with ziprasidone. The primary outcome was change in adherence as measured with the Tablets Routine Questionnaire (TRQ). Secondary outcomes included medication attitudes, BD symptoms, global psychopathology, social functioning, a

SUBMITTER: Sajatovic M 

PROVIDER: S-EPMC4000249 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature