Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study.

ABSTRACT:

Objective

To assess the risk factors for electrographic seizures among neonates treated with therapeutic hypothermia for hypoxic-ischemic encephalopathy (HIE).

Methods

Three-center observational cohort study of 90 term neonates treated with hypothermia, monitored with continuous video-EEG (cEEG) within the first day of life (median age at onset of recording 9.5 hours, interquartile range 6.3-14.5), and continued for >24 hours (total recording 93.3 hours, interquartile range 80.1-112.8 among survivors). A pediatric electroencephalographer at each site reviewed cEEGs for electrographic seizures and initial EEG background category.

Results

A total of 43 (48%) had electrographic seizures, including 9 (10%) with electrographic status epilepticus. Abnormal initial EEG backg

SUBMITTER: Glass HC 

PROVIDER: S-EPMC4001204 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature