Investigation and management of Toxoplasma gondii infection in pregnancy and infancy: a prospective study.

ABSTRACT:

Aim

Toxoplasma gondii infection during pregnancy poses a serious risk to the fetus, therefore timely and accurate diagnosis is essential. The aim of this study was to estimate the frequency of congenital infection via evaluating mother's immunological status and the possibility to improving the diagnostic and therapeutic approaches.

Methods

Eighty five mothers with Toxoplasma seroconversion and their offspring were enrolled (among them, 2 spontaneous abortions were documented in the first trimester). Prenatal PCR diagnosis was carried out on 50 patients (60%), with 7 positive cases (14%). Morphological ultrasound scanning revealed anomalies in one fetus. Long-term follow-up included general physical examinations, serological status tested using Western blot, neuro-radiologic

SUBMITTER: di Carlo P 

PROVIDER: S-EPMC4002529 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature