Ventilator settings and outcome of respiratory failure in chronic interstitial lung disease.

ABSTRACT:

Background

While patients with interstitial lung disease (ILD) may be particularly susceptible to ventilator-induced lung injury, ventilator strategies have not been studied in this group of patients.

Purposes

To describe the clinical course and outcome of patients with ILD and acute respiratory failure in relation to ventilatory parameters.

Methods

We retrospectively identified a cohort of ventilated patients with ILD who had been admitted to five ICUs at a single institution. We analyzed demographic data, pulmonary function test results, severity of illness, and the parameters of continuous ventilation for the initial 24 h after admission to the ICU. Primary outcomes were survival to hospital discharge and 1-year survival.

Main results

Of 94 patients with ILD

SUBMITTER: Fernandez-Perez ER 

PROVIDER: S-EPMC4003484 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature