Decarboxylative arylation of α-amino acids via photoredox catalysis: a one-step conversion of biomass to drug pharmacophore.

ABSTRACT: The direct decarboxylative arylation of α-amino acids has been achieved via visible light-mediated photoredox catalysis. This method offers rapid entry to prevalent benzylic amine architectures from an abundant biomass, specifically α-amino acid precursors. Significant substrate scope is observed with respect to both the amino acid and arene components.

SUBMITTER: Zuo Z 

PROVIDER: S-EPMC4004246 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature