The CJIE1 prophage of Campylobacter jejuni affects protein expression in growth media with and without bile salts.

ABSTRACT:

Background

The presence of Campylobacter jejuni temperate bacteriophages has increasingly been associated with specific biological effects. It has recently been demonstrated that the presence of the prophage CJIE1 is associated with increased adherence and invasion of C. jejuni isolates in cell culture assays.

Results

Quantitative comparative proteomics experiments were undertaken using three closely related isolates with CJIE1 and one isolate without CJIE1 to determine whether there was a corresponding difference in protein expression levels. Initial experiments indicated that about 2% of the total proteins characterized were expressed at different levels in isolates with or without the prophage. Some of these proteins regulated by the presence of CJIE1 were associated with

SUBMITTER: Clark CG 

PROVIDER: S-EPMC4004267 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature