Regression methods for investigating risk factors of chronic kidney disease outcomes: the state of the art.

ABSTRACT:

Background

Chronic kidney disease (CKD) is a progressive and usually irreversible disease. Different types of outcomes are of interest in the course of CKD such as time-to-dialysis, transplantation or decline of the glomerular filtration rate (GFR). Statistical analyses aiming at investigating the association between these outcomes and risk factors raise a number of methodological issues. The objective of this study was to give an overview of these issues and to highlight some statistical methods that can address these topics.

Methods

A literature review of statistical methods published between 2002 and 2012 to investigate risk factors of CKD outcomes was conducted within the Scopus database. The results of the review were used to identify important methodological issues as

SUBMITTER: Boucquemont J 

PROVIDER: S-EPMC4004351 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature