Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery.

ABSTRACT:

Purpose

Desmoplastic small round cell tumor (DSCRT) is an uncommon pediatric tumor with a poor prognosis. Aggressive multimodality therapy is the current treatment approach; however. treatment toxicity is of concern. We report our results with whole abdominopelvic intensity-modulated radiation therapy (WAP-IMRT) as a component of multimodality therapy for DSCRT at a single institution.

Materials/methods

Medical records of all patients with DSCRT who received WAP-IMRT as part of definitive treatment at MD Anderson (2006-2010) were identified and reviewed.

Results

Eight patients with DSRCT received WAP-IMRT with a median follow-up of 15.2 months. All patients received multiple courses of chemotherapy followed by surgical debulking of intra-abdominal disease; seven also

SUBMITTER: Pinnix CC 

PROVIDER: S-EPMC4005898 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature