Species-directed therapy for leishmaniasis in returning travellers: a comprehensive guide.

ABSTRACT:

Background

Leishmaniasis is increasingly reported among travellers. Leishmania species vary in sensitivity to available therapies. Fast and reliable molecular techniques have made species-directed treatment feasible. Many treatment trials have been designed poorly, thus developing evidence-based guidelines for species-directed treatment is difficult. Published guidelines on leishmaniasis in travellers do not aim to be comprehensive or do not quantify overall treatment success for available therapies. We aimed at providing comprehensive species-directed treatment guidelines.

Methodology/principal findings

English literature was searched using PubMed. Trials and observational studies were included if all cases were parasitologically confirmed, the Leishmania species was known,

SUBMITTER: Hodiamont CJ 

PROVIDER: S-EPMC4006727 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature