Higher dietary folate intake reduces the breast cancer risk: a systematic review and meta-analysis.

ABSTRACT:

Background

Many epidemiological studies have investigated the association between folate intake, circulating folate level and risk of breast cancer; however, the findings were inconsistent between the studies.

Methods

We searched the PubMed and MEDLINE databases updated to January, 2014 and performed the systematic review and meta-analysis of the published epidemiological studies to assess the associations between folate intake level, circulating folate level and the overall risk of breast cancer.

Results

In all, 16 eligible prospective studies with a total of 744 068 participants and 26 205 breast cancer patients and 26 case-control studies with a total of 16 826 cases and 21 820 controls that have evaluated the association between folate intake and breast cancer ris

SUBMITTER: Chen P 

PROVIDER: S-EPMC4007237 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature