Reducing aggression and impulsivity through school-based prevention programs: a gene by intervention interaction.

ABSTRACT: A variety of school-based, universal preventive interventions have been developed to address behavioral and mental health problems. Unfortunately, few have been evaluated within the context of randomized controlled trials with long-term follow-up. Even fewer still have examined the potential genetic factors that may drive differential impact of the intervention. In the present analysis, we examine the extent to which the longitudinal effects of two elementary school-based interventions were moderated by the brain-derived neurotrophic factor (BDNF) gene, which has been linked with aggression and impulsive behaviors. The sample included 678 urban, primarily African American children who were randomly assigned along with their teachers to one of three first grade classroom conditions: classro

SUBMITTER: Musci RJ 

PROVIDER: S-EPMC4007396 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature