Transcriptomic analysis of the highly derived radial body plan of a sea urchin.

ABSTRACT: With their complex life cycle and highly derived body plan, echinoderms are unique among bilaterians. Although early development has been intensively studied, the molecular mechanisms underlying development of the adult echinoderm and its unusual radial body plan are largely unknown. To investigate the evolution of developmental changes in gene expression underlying radial body plan development and metamorphosis, we assembled a reference transcriptome de novo and used RNA-seq to measure gene expression profiles across larval, metamorphic, and postmetamorphic life cycle phases in the sea urchin Heliocidaris erythrogramma. Our results present a high-resolution view of gene expression dynamics during the complex transition from pre- to postmetamorphic development and suggest that distinct set

SUBMITTER: Wygoda JA 

PROVIDER: S-EPMC4007537 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature