Comparisons of Shewanella strains based on genome annotations, modeling, and experiments.

ABSTRACT:

Background

Shewanella is a genus of facultatively anaerobic, Gram-negative bacteria that have highly adaptable metabolism which allows them to thrive in diverse environments. This quality makes them an attractive bacterial target for research in bioremediation and microbial fuel cell applications. Constraint-based modeling is a useful tool for helping researchers gain insights into the metabolic capabilities of these bacteria. However, Shewanella oneidensis MR-1 is the only strain with a genome-scale metabolic model constructed out of 21 sequenced Shewanella strains.

Results

In this work, we updated the model for Shewanella oneidensis MR-1 and constructed metabolic models for three other strains, namely Shewanella sp. MR-4, Shewanella sp. W3-18-1, and Shewanella denitrifican

SUBMITTER: Ong WK 

PROVIDER: S-EPMC4007644 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature