Multivariate analysis of correlation between electrophysiological and hemodynamic responses during cognitive processing.

ABSTRACT: Animal and human studies have frequently shown that in primary sensory and motor regions the BOLD signal correlates positively with high-frequency and negatively with low-frequency neuronal activity. However, recent evidence suggests that this relationship may also vary across cortical areas. Detailed knowledge of the possible spectral diversity between electrophysiological and hemodynamic responses across the human cortex would be essential for neural-level interpretation of fMRI data and for informative multimodal combination of electromagnetic and hemodynamic imaging data, especially in cognitive tasks. We applied multivariate partial least squares correlation analysis to MEG-fMRI data recorded in a reading paradigm to determine the correlation patterns between the data types, at once,

SUBMITTER: Kujala J 

PROVIDER: S-EPMC4008646 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature