Dextrose and morrhuate sodium injections (prolotherapy) for knee osteoarthritis: a prospective open-label trial.

ABSTRACT:

Objectives

This study determined whether injection with hypertonic dextrose and morrhuate sodium (prolotherapy) using a pragmatic, clinically determined injection schedule for knee osteoarthritis (KOA) results in improved knee pain, function, and stiffness compared to baseline status.

Design

This was a prospective three-arm uncontrolled study with 1-year follow-up.

Setting

The setting was outpatient.

Participants

The participants were 38 adults who had at least 3 months of symptomatic KOA and who were in the control groups of a prior prolotherapy randomized controlled trial (RCT) (Prior-Control), were ineligible for the RCT (Prior-Ineligible), or were eligible but declined the RCT (Prior-Declined).

Intervention

The injection sessions at occurred at 1, 5,

SUBMITTER: Rabago D 

PROVIDER: S-EPMC4011421 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature