Diastolic function and functional capacity after a single session of continuous positive airway pressure in patients with compensated heart failure.

ABSTRACT:

Objective

The effects of acute continuous positive airway pressure therapy on left ventricular diastolic function and functional capacity in patients with compensated systolic heart failure remain unclear.

Methods

This randomized, double-blind, placebo-controlled clinical trial included 43 patients with heart failure and a left ventricular ejection fraction <0.50 who were in functional classes I-III according to the New York Heart Association criteria. Twenty-three patients were assigned to continuous positive airway pressure therapy (10 cmH2O), while 20 patients received placebo with null pressure for 30 minutes. All patients underwent a 6-minute walk test (6MWT) and Doppler echocardiography before and immediately after intervention. Clinicaltrials.gov: NCT01088854.

Resu

SUBMITTER: Bussoni MF 

PROVIDER: S-EPMC4012238 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature