The feasibility of measuring frailty to predict disability and mortality in older medical intensive care unit survivors.

ABSTRACT:

Purpose

To determine whether frailty can be measured within 4 days prior to hospital discharge in older intensive care unit (ICU) survivors of respiratory failure and whether it is associated with post-discharge disability and mortality.

Materials and methods

We performed a single-center prospective cohort study of 22 medical ICU survivors age 65 years or older who had received noninvasive or invasive mechanical ventilation for at least 24 hours. Frailty was defined as a score of ≥3 using Fried's 5-point scale. We measured disability with the Katz Activities of Daily Living. We estimated unadjusted associations between Fried's frailty score and incident disability at 1-month and 6-month mortality using Cox proportional hazard models.

Results

The mean (SD) age was 77 (

SUBMITTER: Baldwin MR 

PROVIDER: S-EPMC4012557 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature