Risks for early substance involvement associated with parental alcoholism and parental separation in an adolescent female cohort.

ABSTRACT:

Background

We examined timing of substance involvement as a joint function of parental history of alcoholism and parental separation during childhood.

Method

Data were drawn from a large cohort of female like-sex twins [n=613 African Ancestry (AA), n=3550 European or other ancestry (EA)]. Cox proportional hazards regression was conducted predicting age at first use of alcohol, first alcohol intoxication, first use and regular use of cigarettes, and first use of cannabis and other illicit drugs from dummy variables coding for parental alcoholism and parental separation. Propensity score analysis was also conducted comparing intact and separated families by predicted probability of parental separation.

Results

In EA families, increased risk of substance involvement was

SUBMITTER: Waldron M 

PROVIDER: S-EPMC4012919 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature