Prenatal phthalate exposures and neurobehavioral development scores in boys and girls at 6-10 years of age.

ABSTRACT:

Background

There is concern over potential neurobehavioral effects of prenatal phthalate exposures, but available data are inconsistent.

Objectives

We examined associations between prenatal urinary concentrations of phthalate metabolites and neurobehavioral scores among children.

Methods

We measured phthalate metabolite concentrations in urine samples from 153 pregnant participants in the Study for Future Families, a multicenter cohort study. Mothers completed the Child Behavior Checklist when the children were 6-10 years of age. We estimated overall and sex-specific associations between phthalate concentrations and behavior using adjusted multiple regression interaction models.

Results

In boys, concentrations of monoisobutyl phthalate were associated with high

SUBMITTER: Kobrosly RW 

PROVIDER: S-EPMC4014764 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature