Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study.

ABSTRACT:

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Aims/Introduction:  The efficacy, dose-response relationship and safety of ginsam, a vinegar extract from Panax ginseng, were evaluated in an 8-week, double-blind, randomized, placebo-controlled study in drug-naïve patients with type 2 diabetes.

Materials and methods

  A total of 72 diabetic patients were randomized to receive 1500, 2000 or 3000 mg of ginsam, or placebo daily for 8 weeks (n = 18 in each group). The primary end-point was the changes from the baseline HbA1c level. The secondary end-points were the changes of fasting and postprandial 2-h glucose concentration, and the proportion of patients achieving a reduction in HbA1c >0.5%.

Results

  In the intention-to-treat analysis, ginsam treatment reduced HbA1c level significantly: -0.56 ± 0.25% in th

SUBMITTER: Yoon JW 

PROVIDER: S-EPMC4014955 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature