Prequit fMRI responses to pleasant cues and cigarette-related cues predict smoking cessation outcome.

ABSTRACT:

Introduction

The reasons that some smokers find it harder to quit than others are unclear. Understanding how individual differences predict smoking cessation outcomes may allow the development of more successful personalized treatments for nicotine dependence. Theoretical models suggest that drug users might be characterized by increased sensitivity to drug cues and by reduced sensitivity to nondrug-related natural rewards. We hypothesized that baseline differences in brain sensitivity to natural rewards and cigarette-related cues would predict the outcome of a smoking cessation attempt.

Methods

Using functional magnetic resonance imaging, we recorded prequit brain responses to neutral, emotional (pleasant and unpleasant), and cigarette-related cues from 55 smokers intereste

SUBMITTER: Versace F 

PROVIDER: S-EPMC4015090 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature