Patterns of genetic differentiation at MHC class I genes and microsatellites identify conservation units in the giant panda.

ABSTRACT:

Background

Evaluating patterns of genetic variation is important to identify conservation units (i.e., evolutionarily significant units [ESUs], management units [MUs], and adaptive units [AUs]) in endangered species. While neutral markers could be used to infer population history, their application in the estimation of adaptive variation is limited. The capacity to adapt to various environments is vital for the long-term survival of endangered species. Hence, analysis of adaptive loci, such as the major histocompatibility complex (MHC) genes, is critical for conservation genetics studies. Here, we investigated 4 classical MHC class I genes (Aime-C, Aime-F, Aime-I, and Aime-L) and 8 microsatellites to infer patterns of genetic variation in the giant panda (Ailuropoda melanoleuca) an

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC4015443 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature