Parallel deep transcriptome and proteome analysis of zebrafish larvae.

ABSTRACT:

Background

Sensitivity and throughput of transcriptomic and proteomic technologies have advanced tremendously in recent years. With the use of deep sequencing of RNA samples (RNA-seq) and mass spectrometry technology for protein identification and quantitation, it is now feasible to compare gene and protein expression on a massive scale and for any organism for which genomic data is available. Although these technologies are currently applied to many research questions in various model systems ranging from cell cultures to the entire organism level, there are few comparative studies of these technologies in the same system, let alone on the same samples. Here we present a comparison between gene and protein expression in embryos of zebrafish, which is an upcoming model in disease s

SUBMITTER: Palmblad M 

PROVIDER: S-EPMC4016144 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature