Air pollution and cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis.

ABSTRACT: Research to date demonstrates a relationship between exposure to ambient air pollutants and cardiovascular disease (CVD). Many studies have shown associations between short-term exposures to elevated levels of air pollutants and CVD events, and several cohort studies suggest effects of long-term exposure on cardiovascular mortality, coronary heart disease events, and stroke. The biologic mechanisms underlying this long-term exposure relationship are not entirely clear but are hypothesized to include systemic inflammation, autonomic nervous system imbalance, changes in vascular compliance, altered cardiac structure, and development of atherosclerosis. The Multi-Ethnic Study of Atherosclerosis provides an especially well-characterized population in which to investigate the relationship betwe

SUBMITTER: Gill EA 

PROVIDER: S-EPMC4016948 | biostudies-literature | 2011 Mar-Apr

REPOSITORIES: biostudies-literature