Polymorphism in two short tandem repeat loci (R-R and S-Q) linked to tRNA genes in Entamoeba dispar isolates.

ABSTRACT:

Aim

In this study, genetic polymorphism of two tRNA-liked short tandem repeat (STR)-containing loci, R-R and S-Q, was analyzed in order to clarify further the genotypic differences among E. dispar isolates.

Background

Entamoeba dispar is closely related to the human pathogen E. histolytica, the agent of amebic dysentery and amebic liver abscesses. E. dispar is, to some extent, capable of producing variable focal intestinal lesions in animals and of destroying epithelial cell monolayers in vitro, and some have reported it to be capable of producing amoebic liver abscess in hamsters. However no evidence exists at present to link E. dispar with human disease.

Patients and methods

A total of 28 E. dispar samples from gastrointestinal disorder patients were characterized u

SUBMITTER: Nazemalhosseini Mojarad E 

PROVIDER: S-EPMC4017464 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature