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ABSTRACT: Background
A relationship between hypothyroidism and depression has been assumed for many years; however, the true nature of this association has been difficult to define with many conflicting studies. In recent years, our knowledge in this area has increased significantly with large cohort studies and genetically driven studies being published.Objectives
We reviewed the literature on thyroid function and depression to determine if this relationship has been clarified.Methods
We performed a search on the Pubmed database using the terms 'thyroid
' and 'mental health
', 'depression
' and 'well-being
'.Results
Large epidemiological studies generally suggest no association between thyroid function and depression in subjects without thyroid disease. Subjects
SUBMITTER: Dayan CM
PROVIDER: S-EPMC4017747 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature