Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner.
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ABSTRACT:
SUBMITTER: Vasilopoulou E
PROVIDER: S-EPMC4017942 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
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Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner.
Vasilopoulou E E Loubière L S LS Lash G E GE Ohizua O O McCabe C J CJ Franklyn J A JA Kilby M D MD Chan S Y SY
Human reproduction (Oxford, England) 20140313 6
<h4>Study question</h4>Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early pregnancy?<h4>Summary answer</h4>T3 modulates the secretion of specific angiogenic growth factors and cytokines, with different regulatory patterns observed amongst various isolated subpopulations of human decidual cells and with a distinct change between the first and second trimesters of pregnancy.<h4>What is known already</h4>Maternal ...[more]
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