Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140.

ABSTRACT: This report describes the discovery of RAD140, a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). The characterization of RAD140 in several preclinical models of anabolic androgen action is also described.

SUBMITTER: Miller CP 

PROVIDER: S-EPMC4018048 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature