Single-digit arithmetic processing-anatomical evidence from statistical voxel-based lesion analysis.

ABSTRACT: Different specific mechanisms have been suggested for solving single-digit arithmetic operations. However, the neural correlates underlying basic arithmetic (multiplication, addition, subtraction) are still under debate. In the present study, we systematically assessed single-digit arithmetic in a group of acute stroke patients (n = 45) with circumscribed left- or right-hemispheric brain lesions. Lesion sites significantly related to impaired performance were found only in the left-hemisphere damaged (LHD) group. Deficits in multiplication and addition were related to subcortical/white matter brain regions differing from those for subtraction tasks, corroborating the notion of distinct processing pathways for different arithmetic tasks. Additionally, our results further point to the import

SUBMITTER: Mihulowicz U 

PROVIDER: S-EPMC4019872 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature