Improved visibility of character conflicts in quasi-median networks with the EMPOP NETWORK software.

ABSTRACT:

Aim

To provide a valuable tool for graphical representation of mitochondrial DNA (mtDNA) data that enables visual emphasis on complex substructures within the network to highlight possible ambiguities and errors.

Method

We applied the new NETWORK graphical user interface, available via EMPOP (European DNA Profiling Group Mitochondrial DNA Population Database; www.empop.org) by means of two mtDNA data sets that were submitted for quality control.

Results

The quasi-median network torsi of the two data sets resulted in complex reticulations, suggesting ambiguous data. To check the corresponding raw data, accountable nodes and connecting branches of the network could be identified by highlighting induced subgraphs with concurrent dimming of their complements. This is achi

SUBMITTER: Zimmermann B 

PROVIDER: S-EPMC4020147 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature