Diabetes mellitus, but not small dense low-density lipoprotein, is predictive of cardiovascular disease: A Korean community-based prospective cohort study.

ABSTRACT:

Aims/introduction

Small dense low-density lipoprotein (sdLDL) has been suggested to be a potential risk factor for cardiovascular diseases (CVD).

Materials and methods

We carried out a prospective nested case-control study in the Korean Health and Genome Study. Participants were men and women aged 40-69 years who developed CVD (n = 313), and were matched by age and sex to controls who remained free of CVD (n = 313) during the 8-years follow-up period (from 2001 to 2009). LDL subfractions were analyzed in frozen samples collected from the 626 participants using polyacrylamide tube gel electrophoresis.

Results

Patients with CVD had a significantly higher glycated hemoglobin level compared with the controls (5.72 vs 5.56). The proportion of patients with diabetes mellitu

SUBMITTER: Suh S 

PROVIDER: S-EPMC4020249 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature