A statistical simulation model for field testing of non-target organisms in environmental risk assessment of genetically modified plants.

ABSTRACT: Genetic modification of plants may result in unintended effects causing potentially adverse effects on the environment. A comparative safety assessment is therefore required by authorities, such as the European Food Safety Authority, in which the genetically modified plant is compared with its conventional counterpart. Part of the environmental risk assessment is a comparative field experiment in which the effect on non-target organisms is compared. Statistical analysis of such trials come in two flavors: difference testing and equivalence testing. It is important to know the statistical properties of these, for example, the power to detect environmental change of a given magnitude, before the start of an experiment. Such prospective power analysis can best be studied by means of a statist

SUBMITTER: Goedhart PW 

PROVIDER: S-EPMC4020688 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature