A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment.

ABSTRACT:

Importance

Previous studies suggest cross-sectional associations between a diagnosis of chronic obstructive pulmonary disease (COPD) and mild cognitive impairment (MCI). However, few studies have assessed whether COPD, a potentially modifiable factor, is associated with an increased risk for MCI and whether the relation is specific to the type of MCI.

Objective

To investigate whether a diagnosis of COPD and duration of COPD are associated with an increased risk for incident MCI and MCI subtypes (amnestic MCI [A-MCI] and nonamnestic MCI [NA-MCI]).

Design, setting, and participants

A prospective population-based cohort from the Mayo Clinic Study on Aging. We included 1425 cognitively normal individuals aged 70 to 89 years who were randomly selected from Olmsted County,

SUBMITTER: Singh B 

PROVIDER: S-EPMC4020948 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature