An improved peptide-spectral matching algorithm through distributed search over multiple cores and multiple CPUs.

ABSTRACT:

Background

A real-time peptide-spectrum matching (RT-PSM) algorithm is a database search method to interpret tandem mass spectra (MS/MS) with strict time constraints. Restricted by the hardware and architecture of individual workstation, previous RT-PSM algorithms either are not fast enough to satisfy all real-time system requirements or need to sacrifice the level of inference accuracy to provide the required processing speed.

Results

WE DEVELOP TWO PARALLELIZED ALGORITHMS FOR MS/MS DATA ANALYSIS: a multi-core RT-PSM (MC RT-PSM) algorithm which works on individual workstations and a distributed computing RT-PSM (DC RT-PSM) algorithm which works on a computer cluster. Two data sets are employed to evaulate the performance of our proposed algorithms. The simulation results sh

SUBMITTER: Sun J 

PROVIDER: S-EPMC4021225 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature