The Tc1/mariner transposable element family shapes genetic variation and gene expression in the protist Trichomonas vaginalis.

ABSTRACT:

Background

Trichomonas vaginalis is the most prevalent non-viral sexually transmitted parasite. Although the protist is presumed to reproduce asexually, 60% of its haploid genome contains transposable elements (TEs), known contributors to genome variability. The availability of a draft genome sequence and our collection of >200 global isolates of T. vaginalis facilitate the study and analysis of TE population dynamics and their contribution to genomic variability in this protist.

Results

We present here a pilot study of a subset of class II Tc1/mariner TEs that belong to the T. vaginalis Tvmar1 family. We report the genetic structure of 19 Tvmar1 loci, their ability to encode a full-length transposase protein, and their insertion frequencies in 94 global isolates from seven

SUBMITTER: Bradic M 

PROVIDER: S-EPMC4021607 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature