Analysis of the Wnt gene repertoire in an onychophoran provides new insights into the evolution of segmentation.

ABSTRACT:

Background

The Onychophora are a probable sister group to Arthropoda, one of the most intensively studied animal phyla from a developmental perspective. Pioneering work on the fruit fly Drosophila melanogaster and subsequent investigation of other arthropods has revealed important roles for Wnt genes during many developmental processes in these animals.

Results

We screened the embryonic transcriptome of the onychophoran Euperipatoides kanangrensis and found that at least 11 Wnt genes are expressed during embryogenesis. These genes represent 11 of the 13 known subfamilies of Wnt genes.

Conclusions

Many onychophoran Wnt genes are expressed in segment polarity gene-like patterns, suggesting a general role for these ligands during segment regionalization, as has been desc

SUBMITTER: Hogvall M 

PROVIDER: S-EPMC4021614 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature