A retrospective survey of quality of reporting on randomized controlled trials of metformin for polycystic ovary syndrome.

ABSTRACT:

Background

From previous reviews, there still have been controversies over the effect of metformin (MET) on reproductive function in PCOS patients. The reasons for the inconsistent findings especially lie in the transparency and accuracy of randomized controlled trials (RCTs) reports. However, we could find no data about the quality of RCTs reporting in MET for PCOS. Thus, a retrospective survey related to the quality of reporting in MET for PCOS was conducted.

Methods

A retrospective survey was conducted by two investigators. Two investigators assessed the quality of overall reporting and key methodological factors reporting using items from the CONSORT 2010 statement.

Results

A total of 39 RCTs were included in full text. The median overall quality score was 9, with

SUBMITTER: Chen B 

PROVIDER: S-EPMC4021668 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature