Ventral frontal satiation-mediated responses to food aromas in obese and normal-weight women.

ABSTRACT:

Background

Sensory properties of foods promote and guide consumption in hunger states, whereas satiation should dampen the sensory activation of ingestive behaviors. Such activation may be disordered in obese individuals.

Objective

Using functional magnetic resonance imaging (fMRI), we studied regional brain responses to food odor stimulation in the sated state in obese and normal-weight individuals targeting ventral frontal regions known to be involved in coding for stimulus reward value.

Design

Forty-eight women (25 normal weight; 23 obese) participated in a 2-day (fed compared with fasting) fMRI study while smelling odors of 2 foods and an inedible, nonfood object. Analyses were conducted to permit an examination of both general and sensory-specific satiation (sati

SUBMITTER: Eiler WJ 

PROVIDER: S-EPMC4021781 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature