Synchronous and metachronous breast malignancies: a cross-sectional retrospective study and review of the literature.

ABSTRACT:

Objective

There is increasing interest in patients with metachronous (MBC) and synchronous breast cancer (SBC). The objective of this study was to evaluate the occurrence and outcome of MBCs and SBCs.

Methods

A retrospective study on women operated in our department for breast cancer between 2002 and 2005 was carried out. Patients were divided into three groups: women with MBC, SBC, and unilateral breast cancer (UBC). Moreover, we performed a meta-analysis of the English literature about multiple breast cancers between 2000 and 2011 taking into consideration their prevalence and overall survival (OS).

Results

We identified 584 breast cancer patients: 16 women (3%) presented SBC and 40 MBC (7%, second cancer after 72-month follow-up IQR 40-145). Although the meta-analy

SUBMITTER: Londero AP 

PROVIDER: S-EPMC4022260 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature